TPMT (THIOPURINE S-METHYLTRANSFERASE) GENOTYPE / EDTA BLOOD

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This test analyzes the TPMT gene to identify genetic variations that affect thiopurine drug metabolism. Detecting these variants helps determine safe and effective dosing of medications such as azathioprine, 6-mercaptopurine, and 6-thioguanine. Metropolis Healthcare uses advanced molecular techniques to provide accurate genotyping results. The findings help prevent drug toxicity and guide personalized treatment planning

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Price: Rs. 6,095.00

Sample Type: EDTA BLOOD

Fasting Not Required


Booking Procedure:
  1. Technician from Metropolis will be assigned for a home sample collection after booking confirmation.
  2. Sample will be collected by our technician at your address at given slot.
  3. You can make the payment to the technician at the time of collection
  4. Your sample will then be transported to the nearest collection center and will be centrifuged before sending to the lab for processing.
  5. Soft copy reports will be sent to your email address within 24 to 48 hours or as per defined TAT for Tests.

Frequently Asked Questions (FAQ's):

What does the TPMT genotype test include at Metropolis Healthcare?
It examines specific TPMT gene variants that influence how the body processes thiopurine medications.

Why is the TPMT genotyping test important at Metropolis Healthcare?
It helps prevent severe drug toxicity by identifying individuals with reduced or absent TPMT activity.

How does Metropolis Healthcare perform this test?
Sensitive molecular methods such as PCR-based genotyping are used for precise variant detection.

Who should take this test at Metropolis Healthcare?
Patients scheduled to start thiopurine therapy for autoimmune diseases, cancers, or transplant care.

Is any preparation needed for this test?
No fasting or special preparation is required for EDTA blood collection.

How soon are results available from Metropolis Healthcare?
Reports are typically delivered within the standard molecular genetics turnaround time.

What do abnormal TPMT genotypes indicate in Metropolis Healthcare reports?
Variants suggest partial or complete TPMT deficiency, requiring dose adjustment or alternative therapy.

Can this test be combined with other pharmacogenetic tests at Metropolis Healthcare?

Yes, it is often paired with NUDT15 genotyping for comprehensive thiopurine safety assessment 

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