TPMT (THIOPURINE -METHYLTRANSFERASE) ENZYME ACTIVITY / EDTA BLOOD

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This test measures the enzyme activity of TPMT, which plays a crucial role in the metabolism of thiopurine medications. Assessing TPMT activity helps determine how efficiently the body can process drugs such as azathioprine, 6-mercaptopurine, and 6-thioguanine. Reduced activity increases the risk of drug toxicity, while normal activity supports standard dosing. Metropolis Healthcare provides accurate enzymatic analysis to guide safe and personalized therapy 

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Price: Rs. 4,900.00

Sample Type: EDTA BLOOD

Fasting Not Required


Notes: T0098

Frequently Asked Questions (FAQ's):

What does the TPMT enzyme activity test measure at Metropolis Healthcare?
It evaluates the functional activity of the TPMT enzyme in blood to determine thiopurine-metabolizing capacity.

Why is this test important at Metropolis Healthcare?
It helps prevent life-threatening bone marrow toxicity by identifying patients with low or absent TPMT activity before starting therapy.

How is the test performed at Metropolis Healthcare?
A blood sample collected in an EDTA vial is analyzed using standardized biochemical assays to quantify enzyme activity.

Who should undergo this test at Metropolis Healthcare?
Patients who are about to begin thiopurine-based treatment for autoimmune disorders, cancers, or organ transplant care.

Is any preparation required?
No fasting or special preparation is needed for this test.

How soon are the results available at Metropolis Healthcare?
Results are typically provided within the routine turnaround time for enzymatic assays.

What do low TPMT enzyme levels indicate?
They suggest intermediate or deficient metabolizer status, requiring dose adjustments or alternative medications.

Can TPMT enzyme activity be tested along with TPMT genotyping?

Yes, combining both tests offers a more comprehensive assessment of thiopurine drug tolerance and safety 

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