NOTCH 3 (CADASIL) GENE PANEL BY NGS, EDTA BLOOD

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The NOTCH3 (CADASIL) Gene Panel by NGS is a highly specialized genetic test used to detect mutations in the NOTCH3 gene that cause CADASIL (Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy). This inherited disorder affects blood vessels in the brain and can lead to recurrent strokes, migraines with aura, cognitive decline, and early-onset vascular dementia. Metropolis Healthcare utilizes advanced Next-Generation Sequencing technology to analyze EDTA blood samples with high precision for clinically relevant variants. This test is recommended for individuals with unexplained recurrent neurological symptoms, family history of CADASIL, or early stroke-like episodes. Early detection allows effective monitoring, risk management, and preventive care strategies 

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Price: Rs. 20,000.00

Sample Type: EDTA BLOOD

Fasting Not Required


Notes: G0132

Frequently Asked Questions (FAQ's):

What does the NOTCH3 Gene Panel for CADASIL include at Metropolis Healthcare?
It includes targeted sequencing of the NOTCH3 gene to identify mutations associated with CADASIL and related vascular neurological disorders.

How does Metropolis Healthcare perform this genetic test?
Metropolis Healthcare uses high-accuracy NGS platforms and expert genomic analysis to detect pathogenic variants from an EDTA blood sample.

Who should consider taking this test at Metropolis Healthcare?
Individuals with recurrent strokes, chronic migraines, cognitive decline, or a family history of CADASIL should undergo testing.

What sample is needed for the NOTCH3 test at Metropolis Healthcare?
An EDTA blood sample is required for DNA extraction and sequencing.

How long does it take to receive results from Metropolis Healthcare?
Results are typically available within several working days depending on sequencing and data interpretation.

Can this test support clinical management and preventive care?
Yes, Metropolis Healthcare provides mutation details that assist physicians in planning neurological monitoring, lifestyle risk control, and treatment decisions.

Does Metropolis Healthcare offer genetic counseling for CADASIL-related results?
Yes, expert genetic counseling is available to explain the findings and guide family screening and long-term planning.

Is fasting required before giving the blood sample at Metropolis Healthcare?
No, fasting is not required; the sample can be provided at any convenient time

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