DOCK8 (HYPER IGE SYNDROME) GENE PANEL BY NGS, EDTA BLOOD

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The DOCK8 (Hyper IgE Syndrome) Gene Panel by NGS from Metropolis Healthcare analyzes the DOCK8 gene to identify mutations responsible for autosomal recessive Hyper IgE Syndrome. This condition leads to recurrent infections, severe eczema, allergies, and immune dysfunction. The test supports early diagnosis in children and adults with persistent immunodeficiency symptoms. Metropolis Healthcare provides high-accuracy sequencing and expert genetic interpretation to guide appropriate clinical management and counselling

  • 17 Crores+ Samples Processed
  • World Class Technology Labs
  • 25+ Years of Trust & Experience
  • Free Home Collection

Price: Rs. 17,850.00

Sample Type: EDTA BLOOD

Fasting Not Required


Booking Procedure:
  1. Technician from Metropolis will be assigned for a home sample collection after booking confirmation.
  2. Sample will be collected by our technician at your address at given slot.
  3. You can make the payment to the technician at the time of collection
  4. Your sample will then be transported to the nearest collection center and will be centrifuged before sending to the lab for processing.
  5. Soft copy reports will be sent to your email address within 24 to 48 hours or as per defined TAT for Tests.

Frequently Asked Questions (FAQ's):

What does the DOCK8 Gene Panel test look for?
It detects pathogenic variants in the DOCK8 gene associated with Hyper IgE Syndrome using advanced NGS at Metropolis Healthcare.

Who should consider taking this test?
Individuals, especially children, with recurrent infections, severe eczema, allergies, or suspected immunodeficiency.

What sample is needed for this test?
An EDTA blood sample is required for DNA extraction.

How does Metropolis Healthcare perform this test?
Metropolis uses high-depth next-generation sequencing to identify deletions, duplications, and point mutations in the DOCK8 gene.

Can this test help in treatment decisions?
Yes, confirming a DOCK8 mutation supports clinical management, including immune therapy or considering HSCT where appropriate.

Is the test useful for family screening?
Yes, once a mutation is identified, Metropolis Healthcare can perform targeted testing for at-risk relatives.

How long does it take to get results?
Metropolis Healthcare provides accurate reports within a clinically appropriate turnaround time.

Is genetic counselling recommended?
Yes, counselling helps families understand inheritance patterns and long-term care options

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