CYSTIC MEGALENCEPHALY (MLC1) GENE PANEL BY NGS, EDTA BLOOD

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NABL Cap Accredited    
The Cystic Megalencephaly (MLC1) Gene Panel by NGS from Metropolis Healthcare targets the MLC1 gene to detect mutations causing Megalencephalic Leukoencephalopathy with subcortical cysts (MLC). This test is valuable for evaluating children with macrocephaly, developmental delay, seizures, or white-matter abnormalities. It provides a precise genetic diagnosis that supports prognosis, management planning, and family counselling. Metropolis Healthcare uses advanced NGS technology to ensure reliable variant detection and expert interpretation

  • 17 Crores+ Samples Processed
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Price: Rs. 19,950.00

Sample Type: EDTA BLOOD

Fasting Not Required


Notes: G0105

Frequently Asked Questions (FAQ's):

What does the MLC1 Gene Panel test detect?
It identifies pathogenic variants in the MLC1 gene linked to cystic megalencephaly using high-accuracy NGS at Metropolis Healthcare.

Who should undergo this test?
Children with macrocephaly, delayed milestones, seizures, or MRI findings of white-matter changes and subcortical cysts.

What type of sample is needed?
An EDTA blood sample is required for DNA sequencing.

How does Metropolis Healthcare perform this test?
Metropolis uses deep-coverage next-generation sequencing to detect point mutations and small indels in the MLC1 gene.

Can this test help in treatment planning?
Yes, a confirmed genetic diagnosis guides long-term neurological care, symptom management, and monitoring.

Is this test useful for family screening?
Yes, once the mutation is known, Metropolis Healthcare can test siblings or parents for carrier status.

How accurate is this test?
Metropolis Healthcare ensures high sensitivity NGS analysis with expert variant interpretation and reporting.

Is genetic counselling recommended after results?
Yes, counselling supports understanding of inheritance patterns and recurrence risks

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