AGAMMAGLOBULINEMIA (BTK) GENE PANEL BY NGS / EDTA BLOOD

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NABL Cap Accredited    
The Agammaglobulinemia (BTK) Gene Panel by NGS from Metropolis Healthcare detects mutations in the BTK gene, which are responsible for X-linked agammaglobulinemia—a rare immunodeficiency disorder. This condition results in recurrent bacterial infections due to absent or very low B-cell levels and immunoglobulins. The test is performed on an EDTA blood sample using advanced Next Generation Sequencing for precise detection of pathogenic variants. Metropolis Healthcare provides accurate results to support early diagnosis, immunological management, and genetic counselling.

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Price: Rs. 19,950.00

Sample Type: EDTA BLOOD

Fasting Not Required


Notes: G0088

Frequently Asked Questions (FAQ's):

What is Agammaglobulinemia?
It is a rare genetic disorder caused by mutations in the BTK gene, leading to recurrent infections and severely reduced B-cell and antibody levels.

Which gene is tested in this panel?
The BTK gene is analyzed, as mutations in this gene are the primary cause of X-linked agammaglobulinemia.

How does Metropolis Healthcare perform this test?
Metropolis Healthcare uses high-precision NGS technology to detect point mutations, deletions, and duplications in the BTK gene.

What sample type is required?
An EDTA whole blood sample is needed for DNA extraction and sequencing.

Who should consider this test?
Individuals with recurrent bacterial infections, low immunoglobulin levels, or a family history of X-linked agammaglobulinemia.

Is any preparation needed before testing?
No fasting or special preparation is required.

How long do results take at Metropolis Healthcare?
Results are typically available within a few working days depending on laboratory workflow.

How will the results help?
They confirm diagnosis, guide immunoglobulin replacement therapy, and provide information for genetic counselling and family planning.

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